Study on In-Vitro Degradation of Bioabsorbable Polymers Poly (hydroxybutyrate-co-valerate) - (PHBV) and Poly (caprolactone) - (PCL)
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چکیده
منابع مشابه
Films of Poly (L - Lactic Acid) / Poly(Hydroxybutyrate-Co-Hydroxyvalerate) Blends: In vitro Degradation
Biocompatible and biodegradable polymers have been studied in the last few years with good clinical success in the fixation and stabilization of bone fractures. The understanding and the control of the polymeric prosthetic degradation process and the effect of its degradation products in the organism are crucial for the success of the implant. In this present work, blends of PLLA/PHBV, obtained...
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The microbial degradation of tensile test pieces made of poly(3-hydroxybutyrate) [P(3HB)] or a copolymer of 90% 3-hydroxybutyric acid and 10% 3-hydroxyvaleric acid was studied in soils incubated at a constant temperature of 15, 28, or 40 degrees C for up to 200 days. In addition, hydrolytic degradation in sterile buffer at temperatures ranging from 4 to 55 degrees C was monitored for 98 days. D...
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Composite scaffolds were obtained by mixing various amounts (10, 30 and 50 weight % [wt %]) of borosilicate bioactive glass and poly(l-lactide-co-ε-caprolactone) (PLCL) copolymer. The composites were foamed using supercritical CO₂. An increase in the glass content led to a decrease in the pore size and density. In vitro dissolution/reaction test was performed in simulated body fluid. As a funct...
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Microwave irradiation was used to synthesize PEG-PCL and PEG-PLA copolymers that are composed of biodegradable polymers including PEG, PLA, and PCL. These copolymers were used for loading docetaxel in nanoparticles. Single emulsion-solvent evaporation technique was applied for preparing the PEG-PLA and PEG-PCL mixed nanoparticles (micelles and polymersomes) with different proportions, including...
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The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by ...
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ژورنال
عنوان ژورنال: Journal of Biomaterials and Nanobiotechnology
سال: 2011
ISSN: 2158-7027,2158-7043
DOI: 10.4236/jbnb.2011.23026